Variation in growth rate between Arabidopsis ecotypes is correlated with cell division and A-type cyclin-dependent kinase activity

Plant Physiol. 2002 Jun;129(2):854-64. doi: 10.1104/pp.002923.

Abstract

We used a kinematic analysis to investigate the growth processes responsible for variation in primary root growth between 18 ecotypes of Arabidopsis. Root elongation rate differed 4-fold between the slowest (Landsberg erecta, 71 microm h(-1)) and fastest growing line (Wassilewskija [Ws]; 338 microm h(-1)). This difference was contributed almost equally by variations in mature cortical cell length (84 microm [Landsberg erecta] to 237 microm [Ws]) and rate of cell production (0.63 cell h(-1) [NW108] to 1.83 cell h(-1) [Ws]). Cell production, in turn, was determined by variation in cell cycle duration (19 h [Tsu] to 48 h [NW108]) and, to a lesser extent, by differences in the number of dividing cells (32 [Weiningen] to 61 [Ws]). We found no correlation between mature cell size and endoreduplication, refuting the hypothesis that the two are linked. However, there was a strong correlation between cell production rates and the activity of the cyclin-dependent kinase (CDKA). The level of the protein could explain 32% of the variation in CDKA. Therefore, it is likely that regulators of CDKA, such as cyclins and inhibitors, are also involved. These data provide a functional link between cell cycle regulation and whole-plant growth rate as affected by genetic differences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Arabidopsis / classification
  • Arabidopsis / growth & development*
  • Biomechanical Phenomena
  • Cell Cycle / drug effects
  • Cell Cycle / physiology
  • Cell Differentiation / drug effects
  • Cell Differentiation / physiology
  • Cell Division / drug effects
  • Cell Division / physiology
  • Cell Size / drug effects
  • Cell Size / physiology
  • Cyclin-Dependent Kinases / genetics
  • Cyclin-Dependent Kinases / metabolism*
  • Cyclins / pharmacology
  • DNA, Plant / genetics
  • DNA, Plant / metabolism
  • Enzyme Inhibitors / pharmacology
  • Gene Duplication
  • Plant Roots / growth & development
  • Time Factors

Substances

  • Cyclins
  • DNA, Plant
  • Enzyme Inhibitors
  • Cyclin-Dependent Kinases