Remission of transformed myelodysplastic syndrome with fibrosis after danazol therapy

G Damaj; F Lefrère; D Canioni; M T Rubio; I Radford-Weiss; F Valensi; B Varet; O Hermine

doi:10.1034/j.1600-0609.2002.01669.x

Remission of transformed myelodysplastic syndrome with fibrosis after danazol therapy

Eur J Haematol. 2002 Apr;68(4):233-5. doi: 10.1034/j.1600-0609.2002.01669.x.

Authors

G Damaj¹, F Lefrère, D Canioni, M T Rubio, I Radford-Weiss, F Valensi, B Varet, O Hermine

Affiliation

¹ Department of Clinical Hematology, Hôpital Necker Enfants-Malades, Paris, France. [email protected]

PMID: 12071939
DOI: 10.1034/j.1600-0609.2002.01669.x

Abstract

Danazol has been used with success in some hematological diseases, but there is no report of this treatment in acute leukemia. We report here a case of remission of myelodysplastic syndrome with myelofibrosis in transformation after danazol therapy in a 72-yr-old man. The role of danazol in remission induction is briefly discussed.

Publication types

Case Reports

MeSH terms

Aged
Danazol / therapeutic use*
Estrogen Antagonists / therapeutic use*
Humans
Male
Myelodysplastic Syndromes / drug therapy*
Myelodysplastic Syndromes / pathology*
Primary Myelofibrosis / drug therapy*
Remission Induction

Substances

Estrogen Antagonists
Danazol