Tissue-specific knockout model for study of mitochondrial DNA mutation disorders

Methods Enzymol. 2002:353:409-21. doi: 10.1016/s0076-6879(02)53065-2.

Authors

Aleksandra Trifunovic¹, Nils-Göran Larsson

Affiliation

¹ Department of Medical Nutrition, Karolinska Institute, NOVUM, Huddinge Hospital, S-14186 Huddinge, Sweden.

PMID: 12078514
DOI: 10.1016/s0076-6879(02)53065-2

No abstract available

MeSH terms

Animals
DNA, Mitochondrial / genetics*
DNA-Binding Proteins*
Gene Targeting
Genomic Library
High Mobility Group Proteins*
Mice
Mice, Knockout
Mitochondrial Diseases / genetics*
Mitochondrial Diseases / metabolism
Mitochondrial Diseases / pathology
Mutation / genetics*
Organ Specificity
Stem Cells
Trans-Activators*
Transcription Factors / genetics
Transcription Factors / metabolism
Transfection
Xenopus Proteins*

Substances

DNA, Mitochondrial
DNA-Binding Proteins
High Mobility Group Proteins
Tfam protein, mouse
Trans-Activators
Transcription Factors
XL-MTTFA protein, Xenopus
Xenopus Proteins