The goal of this chapter is to present an overview of the main clinical applications of surgical repair in the various anatomical regions of the head. Special consideration will be given to the areas that require reconstruction and to possible problems and complications. Although the skin lesion often dictates the type of incision made, there are various options. The biggest advantage of flaps is the excellent aesthetic result; this is feasible because the skin is similar in color and texture to that being replaced, and moreover no contracture occurs. On the other hand, a flap requires additional incisions and tissue movement, which increases the risks of postoperative complications. The range of flaps that can be used is discussed in detail. Full-thickness skin grafts are an important and necessary tissue source for reconstructive surgery in the face. They must meet the functional and aesthetic challenge posed by the surgical defect and are usually chosen because of the lack of adjacent tissue. Whenever possible, the skin grafts should resemble the surrounding skin in texture, color and thickness.