Correlation between Helicobacter pylori infection and IL-18 mRNA expression in human gastric biopsy specimens

Ann N Y Acad Sci. 2002 Jun:963:326-8. doi: 10.1111/j.1749-6632.2002.tb04125.x.

Abstract

Our data indicate that H. pylori infection is associated with active interleukin-18 production in patients with chronic gastritis. Different cell types appear to be involved in this activity and may play a role in the development of immunopathologic damage.

MeSH terms

  • Biopsy
  • Digestive System / metabolism*
  • Helicobacter Infections / genetics
  • Helicobacter Infections / metabolism*
  • Helicobacter Infections / pathology
  • Helicobacter pylori*
  • Humans
  • Interleukin-18 / genetics
  • Interleukin-18 / metabolism*
  • RNA, Messenger / metabolism
  • Statistics as Topic

Substances

  • Interleukin-18
  • RNA, Messenger