Simulation for population pharmacodynamic analysis of dose-ranging trials: usefulness of the mixture model analysis for detecting nonresponders
Pharm Res
.
2002 Jun;19(6):909-13.
doi: 10.1023/a:1016181505556.
Authors
Takeshi Shiiki
1
,
Yukiya Hashimoto
,
Ken-ichi Inui
Affiliation
1
Pharmacokinetics and Drug Delivery Research Laboratories, Sankyo Co, Ltd, Tokyo, Japan.
PMID:
12134965
DOI:
10.1023/a:1016181505556
No abstract available
Publication types
Evaluation Study
Research Support, Non-U.S. Gov't
MeSH terms
Computer Simulation*
Dose-Response Relationship, Drug
Humans
Models, Biological*
Models, Chemical*
Technology, Pharmaceutical / methods