Primary granulocytic sarcoma of the urinary bladder: case report and review of the literature

Urology. 2002 Aug;60(2):345. doi: 10.1016/s0090-4295(02)01750-8.

Abstract

We report a case of granulocytic sarcoma of the urinary bladder, with no evidence of hematologic involvement. The patient was initially misdiagnosed and was treated with chemotherapy for transitional carcinoma grade 3. Despite this treatment, the clinical features of the patient progressed, and a repeated biopsy yielded the correct diagnosis. Three cases of granulocytic sarcoma of the urinary bladder have been reported in published studies, with only one of these primary. To our knowledge, ours is the second case of granulocytic sarcoma of the urinary bladder presenting with urologic symptoms but without hematologic findings.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cisplatin / administration & dosage
  • Cytarabine / administration & dosage
  • Doxorubicin / administration & dosage
  • Fatal Outcome
  • Humans
  • Idarubicin / administration & dosage
  • Male
  • Methotrexate / administration & dosage
  • Sarcoma, Myeloid* / drug therapy
  • Sarcoma, Myeloid* / pathology
  • Urinary Bladder Neoplasms* / drug therapy
  • Urinary Bladder Neoplasms* / pathology
  • Vinblastine / administration & dosage

Substances

  • Cytarabine
  • Vinblastine
  • Doxorubicin
  • Cisplatin
  • Methotrexate
  • Idarubicin

Supplementary concepts

  • M-VAC protocol