Checking that replication breakdown is not terminal

Science. 2002 Jul 26;297(5581):557-8. doi: 10.1126/science.1075456.

Abstract

Two new studies help to clarify the relationship between checkpoint proteins, recombination, and replication fork integrity.

Publication types

  • Comment

MeSH terms

  • Ataxia Telangiectasia Mutated Proteins
  • Cell Cycle Proteins / metabolism
  • Chromosome Breakage
  • DNA / metabolism
  • DNA Damage*
  • DNA Replication*
  • DNA, Fungal / biosynthesis
  • DNA, Fungal / metabolism*
  • DNA, Single-Stranded / metabolism*
  • Fungal Proteins / metabolism*
  • Intracellular Signaling Peptides and Proteins
  • Models, Biological
  • Protein Serine-Threonine Kinases*
  • Recombination, Genetic*
  • Ribonucleotide Reductases / metabolism
  • S Phase
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism*
  • Saccharomyces cerevisiae Proteins / metabolism
  • Schizosaccharomyces / metabolism
  • Schizosaccharomyces / physiology

Substances

  • Cell Cycle Proteins
  • DNA, Fungal
  • DNA, Single-Stranded
  • Fungal Proteins
  • Intracellular Signaling Peptides and Proteins
  • Saccharomyces cerevisiae Proteins
  • DNA
  • Ribonucleotide Reductases
  • ATR protein, human
  • Ataxia Telangiectasia Mutated Proteins
  • MEC1 protein, S cerevisiae
  • Protein Serine-Threonine Kinases