Abstract
The case of a 61-year-old woman with Whipple's disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipple's disease is discussed.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Actinobacteria / classification
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Actinobacteria / genetics
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Actinobacteria / isolation & purification*
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Actinomycetales Infections / complications
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Actinomycetales Infections / microbiology*
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DNA, Ribosomal / analysis
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Female
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Humans
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Intestinal Mucosa / microbiology
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Intestinal Mucosa / ultrastructure
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Jejunal Diseases / complications
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Jejunal Diseases / microbiology*
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Jejunum
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Middle Aged
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Molecular Sequence Data
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RNA, Ribosomal, 16S / genetics
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Sequence Analysis, DNA
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Sjogren's Syndrome / complications
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Sjogren's Syndrome / microbiology*
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Whipple Disease / complications
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Whipple Disease / microbiology*
Substances
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DNA, Ribosomal
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RNA, Ribosomal, 16S