Innovative minimally invasive pediatric surgery is of therapeutic value for splenic injury

J Pediatr Surg. 2002 Aug;37(8):1146-50. doi: 10.1053/jpsu.2002.34460.

Abstract

Background/purpose: Until now, minimally invasive surgery (MIS) has not had any therapeutic status for operable splenic trauma, because reliable sealing of larger defects is not possible with general techniques.

Methods: Fleece-bound sealing allows rapid, large-area sealing of erosions and defects, so that with the aid of an MIS applicator system (AMISA), this method of tissue management can be transferred to MIS.

Results: An in vitro evaluation showed that liquid fibrin sealing (FS) exhibits incomplete selective leak closure and low adhesive strength (4.1 hPa) and is not suitable for challenging surfaces. Fleece-bound sealing (ready-to-use v. prepare-to-use) showed reliable sealing and higher adhesive strength for collagen fleeces that are ready coated with fibrinogen-based sealant (TachoComb H; Nycomed, Linz, Austria) compared with various carrier systems that had to be impregnated on the spot (prepare-to-use; 50.2 v 23 hPa; P <.0001). Between October 1993 and October 2001, 19 of 87 children with splenic rupture were treated with the AMISA system (AMISA + TachoComb H) (21.8%), and 3 of these children had multiple trauma. The operation was indicated because of circulatory instability despite adequate volume replacement therapy. Splenic repair always was possible with the AMISA system, a changeover and splenectomy was not necessary, and the postoperative course was complication free. The mean stay in the hospital was 9.2 days.

Conclusions: The AMISA system efficiently expands the indications for emergency laparoscopy and can be used successfully in emergency laparoscopy for splenic rupture management.

MeSH terms

  • Adolescent
  • Aprotinin
  • Child
  • Child, Preschool
  • Drainage / methods
  • Drug Combinations
  • Female
  • Fibrin Tissue Adhesive
  • Fibrinogen
  • Hemostasis, Surgical
  • Humans
  • Infant
  • Length of Stay
  • Male
  • Minimally Invasive Surgical Procedures / methods*
  • Postoperative Care
  • Splenic Rupture / surgery*
  • Thrombin
  • Treatment Outcome

Substances

  • Drug Combinations
  • Fibrin Tissue Adhesive
  • tachocomb
  • Fibrinogen
  • Aprotinin
  • Thrombin