Congenital dyserythropoietic anaemia type II: a case study

Acta Clin Belg. 2002 Mar-Apr;57(2):85-9. doi: 10.1179/acb.2002.019.

Abstract

A 13-year-old girl with chronic anaemia showed features of congenital dyserythropoietic anaemia (CDA) type II. The main clinical and haematological findings were splenomegaly, a mild microcytic anaemia, and numerous bizarre and binucleate normoblasts in the bone marrow. The acidified serum lysis test (Ham's test) performed with 5 normal sera was positive. The patient's red blood cells showed a markedly increased expression of the i red blood cell antigen.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anemia, Dyserythropoietic, Congenital / diagnosis*
  • Anemia, Dyserythropoietic, Congenital / genetics
  • Female
  • Humans