Abstract
White family transporters are a group of ATP-binding cassette (ABC) proteins that show sequence homology to the Drosophila white gene product. The Drosophila protein is a subunit of heterodimeric transporters of precursors for eye-pigment synthesis. A novel, human member of this family (ABCG4) has been identified. Northern blotting shows that ABCG4 is expressed specifically in the brain and the eye.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ATP Binding Cassette Transporter, Subfamily G
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ATP-Binding Cassette Transporters / biosynthesis*
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ATP-Binding Cassette Transporters / genetics
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Amino Acid Sequence
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Animals
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Brain / metabolism*
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Drosophila Proteins / chemistry
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Eye / metabolism*
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Eye Proteins / chemistry
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Gene Expression
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Humans
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Molecular Sequence Data
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Sequence Homology, Amino Acid
Substances
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ABCG4 protein, human
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ATP Binding Cassette Transporter, Subfamily G
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ATP-Binding Cassette Transporters
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Drosophila Proteins
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Eye Proteins
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w protein, Drosophila