Survey of the influence of Chinese medicinal prescriptions on amylase activity in mouse plasma and gastrointestinal tube

Biol Pharm Bull. 2002 Aug;25(8):1108-11. doi: 10.1248/bpb.25.1108.

Abstract

Chinese medicinal prescriptions were screened for their effects on alpha-amylase activity in mouse plasma. Daio-kanzo-to, Hange-koboku-to, Saiko-ka-ryukotsu-borei-to, Saiko-keishi-kankyo-to and Mao-to changed the activity in isolated mouse plasma greatly and concentration dependently. However, no prescription influenced the elevation of postprandial blood glucose.

MeSH terms

  • Animals
  • Data Collection / statistics & numerical data*
  • Digestive System / drug effects*
  • Digestive System / enzymology
  • Drug Prescriptions / statistics & numerical data
  • Drugs, Chinese Herbal / pharmacology*
  • Male
  • Mice
  • Pharmaceutical Preparations / metabolism
  • alpha-Amylases / antagonists & inhibitors
  • alpha-Amylases / blood*
  • alpha-Amylases / metabolism

Substances

  • Drugs, Chinese Herbal
  • Pharmaceutical Preparations
  • alpha-Amylases