The efficiency of two-dimensional homonuclear (1)H-(1)H correlated spectroscopy (COSY) and two-dimensional reverse heteronuclear shift correlation spectroscopy (i.e. heteronuclear multiple quantum correlation, HMQC) in characterising the content of the constituents of innovative extracts is demonstrated. These experiments were performed directly on a supercritical carbon dioxide (CO(2)) commercial extract of arnica and were able to fully characterise the active constituents, sesquiterpenes, and other metabolites extracted with the supercritical CO(2), namely polyketides. Identification of constituents was performed by combining literature data and information obtained by 2D-NMR experiments.