Cerebral aspergillosis caused by Neosartorya hiratsukae, Brazil

Emerg Infect Dis. 2002 Sep;8(9):989-91. doi: 10.3201/eid0809.020073.

Abstract

We report the first case of infection by Neosartorya hiratsukae, an ascomycete in which the conidial state resembles Aspergillus fumigatus. The fungus caused a brain infection in a Brazilian woman, who died despite itraconazole treatment. Diagnosis was established by direct microscopic examination, computed tomographic scan, and magnetic resonance imaging of the brain, and repeated cultures from the lesions. The in vitro antifungal susceptibility of the isolate is provided.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Aspergillosis
  • Brazil
  • Central Nervous System Infections / drug therapy
  • Central Nervous System Infections / microbiology
  • Female
  • Fungi / classification*
  • Fungi / isolation & purification*
  • Fungi / pathogenicity
  • Humans
  • Itraconazole / therapeutic use
  • Mycoses / drug therapy
  • Mycoses / microbiology*

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B