Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome

Leukemia. 2002 Sep;16(9):1866-7. doi: 10.1038/sj.leu.2402612.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Aberrations
  • Codon
  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins / genetics*
  • Down Syndrome / complications*
  • Down Syndrome / genetics*
  • Female
  • Humans
  • Infant, Newborn
  • Karyotyping
  • Leukemia / etiology
  • Leukemia / genetics
  • Mutation / genetics*
  • Myeloproliferative Disorders / complications*
  • Myeloproliferative Disorders / genetics*
  • Polymerase Chain Reaction
  • Polymorphism, Single-Stranded Conformational
  • Proto-Oncogene Proteins*
  • Time Factors
  • Transcription Factors / genetics*

Substances

  • Codon
  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins
  • Proto-Oncogene Proteins
  • RUNX1 protein, human
  • Transcription Factors