Point-of-care testing of blood glucose in the neonatal unit using the AVL Omni 9 analyser

Ann Clin Biochem. 2002 Sep;39(Pt 5):509-12. doi: 10.1258/000456302320314539.

Abstract

Background: Blood glucose measurements in newborns at risk of hypoglycaemia are an essential part of their medical management. Blood glucose measurements obtained by point-of-care testing using an AVL Omni 9 blood gas and metabolite analyser were compared with those obtained in the central laboratory using a Dade Dimension RXL analyser.

Methods: Blood glucose was measured at the point of care by nursing staff using an AVL Omni 9 blood gas and metabolite analyser and compared to results obtained in the central laboratory using a DADE Dimension RXL analyser. In total, 123 samples were taken from 114 babies admitted to the neonatal unit.

Results: The limits of agreement between the AVL Omni 9 and the central laboratory were 0.0 +/- 0.6 mmol/L for glucose values between 0.5 and 13 mmol/L. Regression analysis showed: AVL Omni 9 glucose = 0.977 x plasma glucose+0.14. There was also a good correlation (r = 0.92) between the AVL Omni 9 and the DADE Dimension RXL analyser for glucose values < 3 mmol/L. The limits of agreement for the AVL Omni 9 when compared with the DADE Dimension RXL analyser were -0.1 +/- 0.5 mmol/L.

Discussion: Point-of-care testing of blood glucose using the AVL Omni 9 blood gas and metabolite analyser is a reliable means of measuring blood glucose and has the advantage of providing a fast result using small volumes of blood.

Publication types

  • Comparative Study

MeSH terms

  • Biosensing Techniques / instrumentation*
  • Biosensing Techniques / methods*
  • Blood Glucose / analysis*
  • Calibration
  • Hematocrit
  • Humans
  • Hypoglycemia / blood
  • Hypoglycemia / diagnosis
  • Infant, Newborn / blood*
  • Nurseries, Hospital
  • Point-of-Care Systems*
  • Quality Control
  • Regression Analysis

Substances

  • Blood Glucose