A case-control study of HIV-1-related dementia and co-infection with HHV-8

Neurology. 2002 Sep 24;59(6):950-3. doi: 10.1212/wnl.59.6.950.

Abstract

This nested case-control study assessed the putative protective effect of human herpesvirus-8 (HHV-8) against HIV-1-related dementia (dementia). The HHV-8 seropositivity of 210 male age- and HIV disease stage-matched cases and controls was compared. The overall HHV-8 seropositivity of 66% was similar among demented HIV-infected cases and nondemented HIV-infected controls.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS Dementia Complex / blood
  • AIDS Dementia Complex / epidemiology*
  • AIDS Dementia Complex / virology
  • Adult
  • Case-Control Studies
  • Confidence Intervals
  • HIV-1*
  • Herpesvirus 8, Human*
  • Humans
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Odds Ratio
  • Sarcoma, Kaposi / blood
  • Sarcoma, Kaposi / epidemiology*
  • Sarcoma, Kaposi / virology