NMR reporter screening for the detection of high-affinity ligands

Angew Chem Int Ed Engl. 2002 Sep 16;41(18):3420-3. doi: 10.1002/1521-3773(20020916)41:18<3420::AID-ANIE3420>3.0.CO;2-E.
No abstract available

MeSH terms

  • 3-Hydroxysteroid Dehydrogenases / chemistry*
  • 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
  • Benzofurans / chemistry*
  • Drug Design*
  • Enzyme Inhibitors / chemistry*
  • Humans
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Proteins / chemistry*

Substances

  • Benzofurans
  • Enzyme Inhibitors
  • Ligands
  • Proteins
  • 2-acetylbenzofuran
  • 3-Hydroxysteroid Dehydrogenases
  • 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)