PIP: Microbiologists from the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) collected water, sediment, plant, and plankton samples from a lake and a river in Dhaka, Bangladesh to isolate Aeromonas spp. They also took clinical isolates from patients at the Dhaka hospital of ICDDR,B. The microbiologists identified at least 154 isolates of Aeromonas and analyzed them for antibiotic susceptibility using the standard agar disc diffusion method. 92.8% of the environmental isolates and 98.3% of the clinical isolates were resistant to ampicillin. On the other hand, none of the environmental isolates of A. hydrophila and none of the clinical isolates of A. caviae were resistant to chloramphenicol, gentamycin, and kanamycin. Further, 86.3% of clinical A. hydrophila and 95% of A. sobria isolates and 96.1% of environmental A. caviae were also susceptible to chloramphenicol. In addition, 95% of clinical A. sobria isolates were susceptible to gentamycin, while 99.9% of clinical A. hydrophila and 99.9% of environmental A. sobria isolates were susceptible to kanamycin. Resistance of the isolates varied among the remaining antibiotics: 5% resistance to tetracycline for clinical A. sobria isolates to 74.4% resistance to trimethoprim + sulphamethoxazole for environmental A. sobria isolates. Clinicians should note that all the clinical A. hydrophila isolates in this study were resistant to ampicillin and susceptible to chloramphenicol, but this result is different than Daily's research in the early 1980s. Results suggest that chloramphenicol, gentamycin, and kanamycin are effective antibiotics against Aeromonas spp. and that these species worldwide are significantly similar in terms of antibiotic sensitivity patterns.