Constituents of the pollen of Crocus sativus L. and their tyrosinase inhibitory activity

Chem Pharm Bull (Tokyo). 2002 Oct;50(10):1305-9. doi: 10.1248/cpb.50.1305.

Abstract

Five new naturally occurring monoterpenoids, crocusatins-A (1), -B (2a), -C (3), -D (4a) -E (5), a new lactate, sodium (2S)-(O-hydroxyphenyl)lactate (6), and eighteen known compounds were isolated and characterized from the pollen of Crocus sativus L. The tyrosinase inhibitory activities of these compounds were also discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crocus / chemistry*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Enzyme Inhibitors / pharmacology*
  • Monophenol Monooxygenase / antagonists & inhibitors*
  • Monophenol Monooxygenase / metabolism
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Pollen / chemistry*

Substances

  • Enzyme Inhibitors
  • Plant Extracts
  • Monophenol Monooxygenase