Background: This study aimed to explore smoking and drinking as risk factors in psoriasis.
Methods: Data collected from 789 psoriasis patients and 789 healthy controls were analyzed to determine whether there was an association between smoking/drinking and psoriasis.
Results: The proportion of male psoriasis patients using tobacco and alcohol was much higher than that of the control group (P < 10(-6)), whereas no statistical differences were found between female smokers and the control group. In general, heavy smokers were more likely to have severe psoriasis.
Conclusion: Tobacco use in patients is correlated with psoriasis.