A luxCDABE-based bioluminescent bioreporter for the detection of phenol

J Ind Microbiol Biotechnol. 2002 Nov;29(5):233-7. doi: 10.1038/sj.jim.7000309.

Abstract

A bioluminescent reporter strain, Acinetobacter sp. DF4-8, was constructed for the detection of phenol by inserting a mopR-like promoter upstream of the Vibrio fischeri bioluminescent luxCDABE gene cassette in a modified mini-Tn5 construct. When introduced into the chromosome of Acinetobacter sp. DF4, the bioreporter produced a sensitive bioluminescent response to phenol at concentrations ranging from 2.5 to 100 ppm. This response was linear (R(2)=0.986) in the range from 20 to 90 ppm. A significant bioluminescent response was also recorded when strain DF4-8 was incubated with slurries from aged, phenol-contaminated soil.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / genetics*
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Genes, Reporter / genetics*
  • Luminescent Measurements
  • Molecular Sequence Data
  • Oxidoreductases*
  • Phenol / analysis*
  • Promoter Regions, Genetic
  • Soil Pollutants / analysis
  • Substrate Specificity
  • Vibrio / genetics*

Substances

  • Bacterial Proteins
  • Soil Pollutants
  • Phenol
  • Oxidoreductases
  • LuxC protein, Bacteria

Associated data

  • GENBANK/Z69251