Hydroxyapatite-based composite for dental implants: an in vivo removal torque experiment

J Biomed Mater Res. 2002;63(6):714-21. doi: 10.1002/jbm.10392.

Abstract

Screw-shaped dental implants were fabricated from commercially pure Ti (c.p. Ti) and HA-based composites. The HA-based composites were fabricated by mixing HA with Al(2)O(3)-coated ZrO(2) powders. The mechanical properties of these composites were enhanced by a factor of 3. These were implanted into the rabbit tibiae and the removal torque to loosen the implants in vivo was measured in order to investigate the osteointegration. After a healing period of 6 weeks, the implants were retrieved with a torque gauge instrument. The HA-based composite implants showed an almost 2-times-higher removal torque when compared to the Ti implants (ANOVA, p < 0.05), indicating excellent biocompatibility to bone. Thus, HA-based composites had not only better mechanical properties but also similar bioactivity as HA itself. It is believed that a HA-based composite is suitable for artificial dental implants.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum Oxide
  • Animals
  • Dental Implants*
  • Dental Materials*
  • Durapatite*
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Osseointegration
  • Rabbits
  • Titanium
  • Torque
  • Zirconium

Substances

  • Dental Implants
  • Dental Materials
  • Durapatite
  • Zirconium
  • Titanium
  • Aluminum Oxide
  • zirconium oxide