Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management

Am Heart J. 2002 Nov;144(5):769-81. doi: 10.1067/mhj.2002.125804.
No abstract available

Publication types

  • Consensus Development Conference
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Action Potentials / drug effects
  • Amino Acid Sequence
  • Anti-Arrhythmia Agents / adverse effects*
  • Anti-Arrhythmia Agents / therapeutic use
  • Cation Transport Proteins*
  • DNA-Binding Proteins*
  • Drug Evaluation, Preclinical
  • ERG1 Potassium Channel
  • Electrocardiography / drug effects
  • Ether-A-Go-Go Potassium Channels
  • Genetic Testing
  • Genotype
  • Humans
  • Long QT Syndrome / chemically induced
  • Long QT Syndrome / genetics*
  • Long QT Syndrome / physiopathology
  • Maryland
  • Molecular Sequence Data
  • Phenotype
  • Potassium Channels / drug effects
  • Potassium Channels / genetics*
  • Potassium Channels, Voltage-Gated*
  • Practice Guidelines as Topic
  • Torsades de Pointes / chemically induced*
  • Trans-Activators*
  • Transcriptional Regulator ERG

Substances

  • Anti-Arrhythmia Agents
  • Cation Transport Proteins
  • DNA-Binding Proteins
  • ERG protein, human
  • ERG1 Potassium Channel
  • Ether-A-Go-Go Potassium Channels
  • KCNH6 protein, human
  • Potassium Channels
  • Potassium Channels, Voltage-Gated
  • Trans-Activators
  • Transcriptional Regulator ERG