Abstract
Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods. [reaction: see text]
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Indicators and Reagents
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Microwaves*
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Peptides / chemical synthesis
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Peptides / chemistry
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Peptoids / chemical synthesis*
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Peptoids / chemistry
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Peptoids / radiation effects
Substances
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Indicators and Reagents
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Peptides
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Peptoids