Mutagenesis testing based on bacterial expression of human P450s

Methods Enzymol. 2002:357:301-10. doi: 10.1016/s0076-6879(02)57688-6.

Authors

Tetsuya Kamataki¹, Ken-Ichi Fujita

Affiliation

¹ Laboratory of Drug Metabolism, Hokkaido University, Kita-ku, Sapporo 060-0812, Japan.

PMID: 12424920
DOI: 10.1016/s0076-6879(02)57688-6

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetyltransferases / genetics
Acetyltransferases / metabolism
Amino Acid Sequence
Animals
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Cytochrome P-450 Enzyme System / genetics*
Cytochrome P-450 Enzyme System / metabolism
Gene Expression
Humans
Molecular Sequence Data
Mutagenicity Tests / methods*
Mutagens / metabolism*
NADPH-Ferrihemoprotein Reductase / genetics
NADPH-Ferrihemoprotein Reductase / metabolism
Plasmids / genetics
Plasmids / metabolism
Salmonella typhimurium / genetics
Salmonella typhimurium / metabolism
Transfection

Substances

Bacterial Proteins
Mutagens
Cytochrome P-450 Enzyme System
NADPH-Ferrihemoprotein Reductase
Acetyltransferases