Inhibition of autoimmune diabetes by mycophenolate mofetil is associated with down-regulation of TH1 cytokine-induced apoptosis in the target tissue

Transplant Proc. 2002 Nov;34(7):2955-7. doi: 10.1016/s0041-1345(02)03502-9.
No abstract available

MeSH terms

  • Animals
  • Apoptosis / drug effects
  • Apoptosis / physiology*
  • Cytokines / immunology*
  • Diabetes Mellitus, Experimental / immunology*
  • Diabetes Mellitus, Experimental / prevention & control
  • Diabetes Mellitus, Type 1 / immunology*
  • Diabetes Mellitus, Type 1 / prevention & control*
  • Disease Models, Animal
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Mice
  • Mice, Inbred CBA
  • Mycophenolic Acid / analogs & derivatives
  • Mycophenolic Acid / therapeutic use*
  • Rats
  • Rats, Inbred Strains
  • Th1 Cells / immunology*

Substances

  • Cytokines
  • Immunosuppressive Agents
  • Mycophenolic Acid