Further isolation of peroxynitrite and 1,1-diphenyl-2-picrylhydrazyl radical scavenging isorhamnetin 7-O-glucoside from the leaves of Brassica juncea L

Arch Pharm Res. 2002 Oct;25(5):625-7. doi: 10.1007/BF02976933.

Abstract

From the leaves of Brassica juncea, an radical scavenging isorhamnetin 7-O-glucoside on peroxynitrite and 1,1-diphenyl-2-picrylhydrazyl (DPPH) was isolated and characterized based on the spectroscopic evidence. The compound showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 +/- 0.17 and 13.3 microM, respectively. Penicillamine and L-ascorbic acid as positive control exhibited radical scavenging activities with IC50 values of 3.17 +/- 0.39 and 12.78 microM, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biphenyl Compounds
  • Flavonols*
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Mustard Plant* / chemistry
  • Peroxynitrous Acid / chemistry
  • Peroxynitrous Acid / isolation & purification*
  • Picrates / chemistry
  • Picrates / isolation & purification*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Leaves
  • Quercetin / analogs & derivatives
  • Quercetin / chemistry
  • Quercetin / isolation & purification*

Substances

  • Biphenyl Compounds
  • Flavonols
  • Free Radical Scavengers
  • Glucosides
  • Picrates
  • Plant Extracts
  • 3-methylquercetin
  • Peroxynitrous Acid
  • Quercetin
  • 1,1-diphenyl-2-picrylhydrazyl