Abstract
The methanol extract of heartwood of Cercidiphyllum japonicum (Cercidiphyllaceae) stimulated proliferation of mouse hair epithelial cells, similar to minoxidil and procyanidin B-2. (+)-Taxifolin ( 2), quercetin ( 3), myricetin ( 4), (+)-dihydromyricetin ( 5) and gallic acid ( 6) were isolated from C. japonicum and showed significant proliferative activities on the hair epithelial cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Biflavonoids*
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Catechin / pharmacology
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Cell Differentiation / drug effects*
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Dose-Response Relationship, Drug
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Epithelial Cells / drug effects
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Flavonoids*
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Hair / cytology*
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Hair / drug effects*
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Mice
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Minoxidil / pharmacology
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Phenols / administration & dosage
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Phenols / chemistry
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Phenols / pharmacology*
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / chemistry
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Plant Extracts / pharmacology*
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Polymers / administration & dosage
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Polymers / chemistry
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Polymers / pharmacology*
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Proanthocyanidins*
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Saxifragaceae*
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Thymidine / metabolism
Substances
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Biflavonoids
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Flavonoids
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Phenols
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Plant Extracts
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Polymers
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Proanthocyanidins
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procyanidin B
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procyanidin
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Minoxidil
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Catechin
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Thymidine