Low grade squamous intra-epithelial lesions and human papillomavirus infection in Colombian women

Br J Cancer. 2002 Dec 2;87(12):1417-21. doi: 10.1038/sj.bjc.6600650.

Abstract

Low grade squamous intra-epithelial lesions could be considered as a manifestation of human papillomavirus exposition, however the discrepancy between rates of infection with human papillomavirus and development of low grade squamous intra-epithelial lesions is notable. Here we report a cross-sectional three-armed case-control study in the Colombian population, to compare the risk factors of women with low grade squamous intra-epithelial lesions with that of human papillomavirus DNA-negative and positive women with normal cytology.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Chlamydia trachomatis / genetics
  • Chlamydia trachomatis / isolation & purification
  • Colombia / epidemiology
  • Cross-Sectional Studies
  • DNA Probes, HPV
  • DNA, Bacterial / analysis
  • DNA, Viral / analysis
  • Female
  • Humans
  • Middle Aged
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / epidemiology
  • Papillomavirus Infections / pathology
  • Papillomavirus Infections / virology*
  • Polymerase Chain Reaction
  • Risk Factors
  • Tumor Virus Infections / epidemiology
  • Tumor Virus Infections / pathology
  • Tumor Virus Infections / virology*
  • Uterine Cervical Dysplasia / epidemiology
  • Uterine Cervical Dysplasia / pathology
  • Uterine Cervical Dysplasia / virology*
  • Uterine Cervical Neoplasms / epidemiology
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / virology*
  • Vaginal Smears / methods

Substances

  • DNA Probes, HPV
  • DNA, Bacterial
  • DNA, Viral