Abstract
Two new oleanane triterpenes; 2alpha,3alpha,24-trihydroxyolean-12-ene-28,30-dioic acid ([structure: see text]) and 2alpha,3alpha,24,28-tetrahydroxyolean-12-ene ([structure: see text]) have been isolated from the roots of Atropa acuminata. Anti-oxidant p-hydroxyphenethyl trans-ferulate ([structure: see text]), beta-sitosterol-3-O-beta-D-glucopyranoside ([structure: see text]) and oleanolic acid ([structure: see text]) have also been reported for the first time from this species. The structures were determined by spectroscopic studies including 2D-NMR.
MeSH terms
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Antioxidants / chemistry
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Antioxidants / isolation & purification*
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Antioxidants / pharmacology
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Atropa / chemistry*
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Coumaric Acids / chemistry
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Coumaric Acids / isolation & purification
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Coumaric Acids / pharmacology
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Glucosides / chemistry
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Glucosides / isolation & purification
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Glucosides / pharmacology
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Inhibitory Concentration 50
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Oleanolic Acid / analogs & derivatives
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Oleanolic Acid / chemistry
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Oleanolic Acid / isolation & purification*
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Oleanolic Acid / pharmacology
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Pakistan
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
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Sitosterols / chemistry
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Sitosterols / isolation & purification
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Sitosterols / pharmacology
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Spectrophotometry, Infrared
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Stereoisomerism
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology
Substances
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2,3,24,28-tetrahydroxyolean-12-ene
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2,3,24-trihydroxyolean-12-ene-28,30-dioic acid
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Antioxidants
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Coumaric Acids
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Glucosides
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Sitosterols
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Triterpenes
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hydroxyphenethylferulate
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sitosterol-3-O-glucopyranoside
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Oleanolic Acid