Abstract
Unique physiological and immunological features of the brain, as previously presented, explain the limitation of local inflammatory reactions and the existence of intrathecal specific IgG production. In addition, some parasitic factors of recent knowledge are induced during neurocysticercosis, which could be involved in vivo in a modulation of the immune response by larval products (a soluble RNA-peptide, some metacestode surface sphingoglycolipids). These recent findings lead us to make a critical review of the antigenic profiles obtained by enzyme-linked immunoelectrotransfer blot (EITB) on samples collected from patients suffering from simple or multiple neurocysticercosis.
MeSH terms
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Adolescent
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Adult
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Aged
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Antibodies, Helminth / blood
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Antibodies, Helminth / cerebrospinal fluid
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Antibodies, Helminth / immunology
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Antigens, Helminth / immunology
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Child
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Child, Preschool
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Enzyme-Linked Immunosorbent Assay
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Female
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Humans
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Immune Tolerance / immunology
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Immunoblotting
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Immunoglobulin G / blood
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Immunoglobulin G / cerebrospinal fluid
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Immunoglobulin G / immunology
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Inflammation / immunology
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Male
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Middle Aged
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Neurocysticercosis / diagnostic imaging
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Neurocysticercosis / immunology*
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Neurocysticercosis / metabolism
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Neurocysticercosis / parasitology
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Sensitivity and Specificity
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Tomography, X-Ray Computed
Substances
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Antibodies, Helminth
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Antigens, Helminth
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Immunoglobulin G