[Sarcoid granuloma simulating amelanotic melanoma of the iris: a case report]

J Fr Ophtalmol. 2002 Oct;25(8):831-4.
[Article in French]

Abstract

We report the case of a unilateral vascular iris tumor in a 24-year-old patient. Clinically, the iris lesion appeared similar to amelanotic melanoma. A systemic work-up (initial check-up), including an angiotensin-converting enzyme determination, provided the diagnosis of sarcoid granuloma. A biopsy confirmation was not needed. We concluded that iris granuloma can be the only ocular manifestation of sarcoidosis and this context is likely to be confused with amelanotic melanoma and metastatic carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Dexamethasone / administration & dosage
  • Dexamethasone / therapeutic use
  • Diagnosis, Differential
  • Follow-Up Studies
  • Glucocorticoids
  • Granuloma / diagnosis*
  • Granuloma / drug therapy
  • Humans
  • Iris Diseases / diagnosis*
  • Iris Diseases / drug therapy
  • Iris Neoplasms / diagnosis*
  • Male
  • Melanoma, Amelanotic / diagnosis*
  • Neomycin / administration & dosage
  • Neomycin / therapeutic use
  • Sarcoidosis / diagnosis*
  • Sarcoidosis / drug therapy
  • Time Factors
  • Visual Acuity

Substances

  • Adrenal Cortex Hormones
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Dexamethasone
  • Neomycin