[Audit of preoperative antibiotic prophylaxis in a surgical site infections surveillance network]

Ann Fr Anesth Reanim. 2002 Oct;21(8):627-33. doi: 10.1016/s0750-7658(02)00705-0.
[Article in French]

Abstract

Objective: To evaluate the preoperative antibiotic prophylaxis (PAP) prescriptions in a surgical site infection (SSI) surveillance network.

Study design: Auto-evaluative audit in a prospective multicenter cohort included in a surveillance system.

Patients and methods: Since 1997, surgical wards in volunteer centers monitored all surgery patients each year during a period of two months. Patients were evaluated for SSI during the 30 days following surgery. Participating centers were asked in 2000 to participate to a PAP practice assessment. For each surgery patient, a questionnaire was completed. The "Guidelines for Antibiotic Prophylaxis Prescription in Surgery" edited in 1999 by the Société française d'anesthésie et de réanimation was used as gold standard.

Results: 6109 patients were included in the survey from 34 health care centers and 3881 received PAP. 90% of patients received PAP intravenously and 63% received twice the curative dose. PAP was administered within 90 minutes prior to incision in 70% of cases. 78% of PAP lasted less than 24 hours. PAP indication with regards to the type of surgical procedures was assessed in 4629 patients. PAP guidelines were observed in 1573 (34%) patients: 999 patients in whom PAP was not indicated did not receive PAP and 574 received it in compliance with recommended dose and indications.

Conclusion: Efforts should be made to improve PAP prescription according to standards guidelines.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Antibiotic Prophylaxis / standards*
  • Antibiotic Prophylaxis / statistics & numerical data
  • Cohort Studies
  • Drug Prescriptions / standards
  • France / epidemiology
  • Guidelines as Topic
  • Humans
  • Medical Audit
  • Surgical Wound Infection / prevention & control*

Substances

  • Anti-Bacterial Agents