The role of folic acid and vitamin B12 in colorectal carcinogenesis in genetically different individuals--design of a study

IARC Sci Publ. 2002:156:499-500.

Authors

M Van den Donk¹, E P M Pellis, J Keijer, F J Kok, F M Nagengast, E Kampman

Affiliation

¹ Wageningen University, Division of Human Nutrition and Epidemiology, The Netherlands.

PMID: 12484242

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenomatous Polyps / enzymology
Adenomatous Polyps / genetics*
Adenomatous Polyps / prevention & control
Case-Control Studies
Colorectal Neoplasms / enzymology
Colorectal Neoplasms / genetics*
Colorectal Neoplasms / prevention & control
DNA / biosynthesis
DNA Methylation / drug effects
Folic Acid / administration & dosage
Folic Acid / metabolism
Folic Acid / physiology*
Gene Expression Regulation, Neoplastic / drug effects
Genotype
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Oligonucleotide Array Sequence Analysis
Oxidoreductases Acting on CH-NH Group Donors / genetics*
Oxidoreductases Acting on CH-NH Group Donors / metabolism
Research Design
Risk Factors
Tumor Cells, Cultured
Vitamin B 12 / administration & dosage
Vitamin B 12 / physiology*

Substances

DNA
Folic Acid
Oxidoreductases Acting on CH-NH Group Donors
Methylenetetrahydrofolate Reductase (NADPH2)
Vitamin B 12