Retinal arteriolar obstruction with progestogen treatment of threatened abortion

Acta Ophthalmol Scand. 2002 Dec;80(6):667-8. doi: 10.1034/j.1600-0420.2002.800621.x.

Abstract

Purpose: To describe a case of a retinal arteriolar occlusion associated with progestogen treatment of threatened abortion.

Methods: Case report.

Results: A 30-year-old woman who had received a 2-week course of high dose intramuscular progestogen for a threatened abortion presented with a paracentral scotoma in her right eye and occlusion of a small arteriole adjacent to the macula. There were no major subsequent variations in haemostasis and pre-existing systemic diseases were excluded.

Conclusions: Retinal arteriolar occlusion may be associated with high dose progestogen-only therapy in pregnant women.

MeSH terms

  • Abortion, Threatened / drug therapy*
  • Adult
  • Arterioles
  • Female
  • Humans
  • Hydroxyprogesterones / adverse effects*
  • Injections, Intramuscular
  • Pregnancy
  • Retinal Artery Occlusion / chemically induced*
  • Retinal Artery Occlusion / diagnosis
  • Scotoma / chemically induced

Substances

  • Hydroxyprogesterones
  • 17-hydroxyprogesterone heptanoate