An extract of Tagetes lucida and its phenolic constituents as antioxidants

J Nat Prod. 2002 Dec;65(12):1773-6. doi: 10.1021/np020018i.

Abstract

Analysis of a methanolic extract of Tagetes lucida leaves has resulted in the isolation of a new flavonol glycoside, quercetagenin 3,4'-dimethyl ether 7-O-beta-D-glucopyranoside (1), two new phenolic acids, 3-(2-O-beta-D-glucopyranosyl-4-methoxyphenyl)propanoic acid (2) and its methylester (3), and known flavonols, aromatic acids, and 7-methoxycoumarin. Using the DPPH degrees test, the extract and some of its constituents showed a significant free-radical-scavenging effect in comparison to alpha-tocopherol and standard flavonols.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Biphenyl Compounds
  • Chromatography, High Pressure Liquid
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Guatemala
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Picrates
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Spectrophotometry, Ultraviolet
  • Tagetes / chemistry*
  • Tocopherols / pharmacology

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Flavonoids
  • Free Radical Scavengers
  • Glycosides
  • Picrates
  • quercetagenin 3,4'-dimethyl ether 7-O-glucopyranoside
  • 1,1-diphenyl-2-picrylhydrazyl
  • Tocopherols