Abstract
A series of scalarane class sesterterpenes (1-8) have been isolated from an Indonesian sponge, Phyllospongia sp. Their structures were determined by spectroscopic analysis and confirmed by single-crystal X-ray diffraction on compound 1. The absolute stereochemistry of 1 was established by modified Mosher's method.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Drug Screening Assays, Antitumor
-
Humans
-
Indonesia
-
KB Cells / drug effects
-
Methylation
-
Molecular Structure
-
Nuclear Magnetic Resonance, Biomolecular
-
Porifera / chemistry*
-
Sesterterpenes
-
Spectroscopy, Fourier Transform Infrared
-
Stereoisomerism
-
Terpenes / chemistry
-
Terpenes / isolation & purification*
-
Terpenes / pharmacology
-
Tumor Cells, Cultured / drug effects
-
X-Ray Diffraction