[Allele polymorphism of molecular-genetic individualizing systems based on tetranucleotide tandem repeats LPL, vWA and TH01 among the population of Russia]

Sud Med Ekspert. 2002 Sep-Oct;45(5):12-4.
[Article in Russian]

Abstract

Until recently, data bases on incidence rates of alleles STR (LPL, vWA and THO1 loci) have not been introduced in Russia. To obtain information on the above rates in Russia, a large scale research of distribution of LPL, vWA and Tho1 loci has been performed among a sample of 442 blood-unrelated persons from 57 regions of the Russian Federation to specify basic assessment characteristics of these loci and to raise efficiency of expert use of identifying systems on their base. Relevant parameters (allele frequencies) are presented for each polymorphic locus as well as basic population characteristics of polymorphism in the studied sample of RF population. These results can be used as key parameters for standard probability estimations in assessing the results of molecular-genetic identification.

Publication types

  • English Abstract

MeSH terms

  • Alleles
  • DNA / analysis
  • Forensic Medicine*
  • Genetics, Population / methods*
  • Humans
  • Microsatellite Repeats / genetics*
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*
  • Russia

Substances

  • DNA