Abstract
To study the relationship between bacterial protective liquid (BPL) and the biological effect of mouse bone marrow cells by gamma-ray irradiation, apoptosis and the number of CD4+, CD8+ and NK cells were analyzed by flow cytometry(FCM), the results showed that BPL decreased the apoptosis and increased the proliferation of cells(P < 0.01). The theorem of action was related with raising the percentage vitality of NK cells and the quantity of CD4+ and CD8+. This study proved that BPL might have protective effect against radiation injury.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Apoptosis / radiation effects*
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Bacillaceae
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Bone Marrow Cells / radiation effects*
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CD4-Positive T-Lymphocytes / immunology
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CD8-Positive T-Lymphocytes / immunology
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Cobalt Radioisotopes
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Female
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Flow Cytometry
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Gamma Rays
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Homocystine
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Killer Cells, Natural / immunology
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Mice
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Radiation Injuries, Experimental / immunology
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Radiation Injuries, Experimental / pathology*
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Radiation-Protective Agents / pharmacology*
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Random Allocation
Substances
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Cobalt Radioisotopes
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Radiation-Protective Agents
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Homocystine