To investigate the allergy reaction of rural residents against 12 categories sensibiligen, 9,232 sensibiligen peasants from rural areas of Anqing were observed by 12 categories sensibiligen in skin(methods: point thron). If the diameter of papule erygthema was bigger than that of histamines of control, the reaction was considered to be positive. All cata was analyzed by sas software. The results showed that the allergy reaction degrees were different among the groups with different genders and ages. Family susceptibility was noticed.