Novel clonal der(8)t(8;14)(p11;q11),del(9)(q13q22) and t(14;22) (q13;q13) in a patient with fulminant adult T-cell leukemia/lymphoma

Cancer Genet Cytogenet. 2002 Nov;139(1):34-7. doi: 10.1016/s0165-4608(02)00621-0.

Abstract

We describe a 70-year-old man with fulminant adult T-cell leukemia/lymphoma. He died of progressive disease 1 week after the onset of symptoms. The integrated viral DNA of human T-lymphotropic virus type I was detected in the bone marrow aspirate by polymerase chain reaction. Cytogenetic analysis of bone marrow cells showed novel clonal aberrations consisting of 46,XY,der(8)t(8;14)(p11;q11),del(9) (q13q22),t(14;22)(q13;q13).

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Base Sequence
  • Chromosome Deletion*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 14*
  • Chromosomes, Human, Pair 22*
  • Chromosomes, Human, Pair 8*
  • Chromosomes, Human, Pair 9*
  • DNA Primers
  • Humans
  • Karyotyping
  • Leukemia-Lymphoma, Adult T-Cell / blood
  • Leukemia-Lymphoma, Adult T-Cell / genetics*
  • Leukemia-Lymphoma, Adult T-Cell / pathology*
  • Male
  • Translocation, Genetic*

Substances

  • DNA Primers