Lymphatic mapping with tracer administration into the primary breast cancer

Eur J Surg Oncol. 2003 Feb;29(1):95-7. doi: 10.1053/ejso.2002.1384.

Abstract

There is an ongoing debate over the best tracer injection technique in lymphatic mapping for breast cancer. The technique of low tracer volume administration into the primary breast cancer is presented. The reasons that led to this approach are explained as well as its advantages. Excision of radioactivity that remains at the injection site in the breast cancer prevents the gamma ray scatter that may hamper retrieval of a sentinel node. The intralesional injection technique avoids potential injection of tracer fluid across a lymphatic watershed, it enables identification of extra-axillary sentinel nodes and allows probe-guided excision of non-palpable tumours.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Injections, Intralymphatic / standards
  • Netherlands
  • Radioactive Tracers*
  • Radiopharmaceuticals / administration & dosage
  • Sentinel Lymph Node Biopsy* / standards
  • Women's Health

Substances

  • Radioactive Tracers
  • Radiopharmaceuticals