Heavy episodic drinking is a relatively common phenomenon among college students, and students who engage in binge drinking are at increased risk for a variety of adverse consequences. This paper investigates relationships between substance use and reinforcement derived from specific categories of substance-free activities among a sample of 256 college undergraduates. Data from a standardized behavioral inventory were used to compare the frequency, pleasure, and reinforcement potential of substance-free events and activities experienced by binge drinkers and a comparison group. Binge drinkers reported significantly lower scores across a variety of substance-free activity categories and, in the majority of the cases, the relationship between binge drinking and decreased reinforcement density remained significant after accounting for the effects of the use of other drugs and demographic variables. These results are consistent with a growing body of evidence linking substance use to deprivation of substance-free reinforcement.