Expression and modification of NO synthase in human dental pulps during orthodontic treatment

Bull Group Int Rech Sci Stomatol Odontol. 2002 May-Sep;44(2):57-60.

Abstract

In the last few years our histology laboratory has worked in collaboration with Winchmore Hill Dental Practice in London in studying nitric oxide synthase (NOS) protein expression by the use of immunohistochemistry in dental pulps following orthodontic treatment (A. Gerbino et al. 2000; A. Gerbino et al 2001; A. Gerbino et al 2001.) The study has been carried out on samples taken from orthodontically treated and non-orthodontically treated teeth. The results suggest a close correlation between the duration of the orthodontic traction and the expression of the above-mentioned neurotransmitter (NO).

MeSH terms

  • Adolescent
  • Antibodies
  • Capillaries / enzymology
  • Child
  • Coloring Agents
  • Dental Pulp / blood supply
  • Dental Pulp / enzymology*
  • Dental Pulp / innervation
  • Female
  • Fluorescent Dyes
  • Gene Expression Regulation, Enzymologic
  • Humans
  • Immunoenzyme Techniques
  • Immunohistochemistry
  • Male
  • Nerve Fibers / enzymology
  • Neurotransmitter Agents / analysis*
  • Neurotransmitter Agents / genetics
  • Nitric Oxide Synthase / analysis*
  • Nitric Oxide Synthase / genetics
  • Odontoblasts / enzymology
  • Time Factors
  • Tooth Movement Techniques*

Substances

  • Antibodies
  • Coloring Agents
  • Fluorescent Dyes
  • Neurotransmitter Agents
  • Nitric Oxide Synthase