[The clinical diagnosis 'wound botulism' in an injecting drug addict]

Ned Tijdschr Geneeskd. 2003 Jan 18;147(3):124-7.
[Article in Dutch]

Abstract

A 38-year-old subcutaneous injecting heroin addict had subacute blurred vision, dysarthria and dysphagia. The next day she could not swallow or speak and developed weakness of all limbs and respiratory failure. Electromyography showed abnormalities compatible with a presynaptic neuromuscular transmission deficit, which supported the diagnosis of botulism. The point of entry was probably a skin abscess due to injections. Treatment with antitoxin and antibiotics resulted in a favourable recovery. Wound botulism is caused by local production of toxin by Clostridium botulinum after wound infection. Although it is a rare variant of botulism, it is increasingly being reported in drug users who inject subcutaneously.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Botulism / diagnosis
  • Botulism / drug therapy
  • Botulism / etiology*
  • Electromyography
  • Female
  • Humans
  • Injections, Subcutaneous / adverse effects
  • Substance Abuse, Intravenous / complications*
  • Wound Infection / microbiology*
  • Wounds and Injuries / etiology
  • Wounds and Injuries / microbiology*