Abstract
No randomized, placebo-controlled studies have investigated interferon-alpha therapy in enterovirus-proven myocarditis. This report describes 2 patients with enterovirus-induced myocarditis (1 with associated Churg-Strauss syndrome) who at follow-up endomyocardial biopsy showed clinical and hemodynamic improvement and viral clearance (using polymerase chain reaction) after interferon-alpha therapy.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Aged
-
Antiviral Agents / therapeutic use*
-
Biopsy
-
Churg-Strauss Syndrome / complications
-
Enterovirus Infections / drug therapy*
-
Humans
-
Interferon alpha-2
-
Interferon-alpha / therapeutic use*
-
Male
-
Myocarditis / complications
-
Myocarditis / drug therapy*
-
Myocarditis / virology
-
Myocardium / pathology
-
Recombinant Proteins
-
Reverse Transcriptase Polymerase Chain Reaction
Substances
-
Antiviral Agents
-
Interferon alpha-2
-
Interferon-alpha
-
Recombinant Proteins