[Experimental study on anti-thrombus effect of different extracts from Semen Persicae]

Zhong Yao Cai. 2002 Jun;25(6):414-5.
[Article in Chinese]

Abstract

Objective: To observe the effects of anti-thrombus of different extracts from Semen Persicae and provide experimental basis for finding and defining effective fraction of Semen Persicae.

Methods: The effects of different extracts from Semen Persicae on clotting time in mice, pulmonary embolism in mice and electro-irritate thrombosis in rats were observed.

Result: Ethyl acetate extract from Semen Persicae could prolong clotting time in mice, markedly relieve respiratory difficult due to pulmonary embolism in mice induced by ADP-Na, obviously retard the generation of thrombosis induced by electrical injury of carotid artery in rats.

Conclusion: Ethyl acetate extract from Semen Persicae possesses evidently anti-thrombotic effect.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Carotid Artery Thrombosis / prevention & control*
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / therapeutic use*
  • Fibrinolytic Agents / isolation & purification
  • Fibrinolytic Agents / therapeutic use*
  • Mice
  • Phytotherapy*
  • Plants, Medicinal / chemistry
  • Prunus / chemistry*
  • Pulmonary Embolism / drug therapy
  • Rats
  • Rats, Wistar
  • Seeds / chemistry
  • Whole Blood Coagulation Time

Substances

  • Drugs, Chinese Herbal
  • Fibrinolytic Agents