Conservative management of placenta accreta and unruptured interstitial cornual pregnancy using methotrexate

Eur J Obstet Gynecol Reprod Biol. 2003 Mar 26;107(1):96-7. doi: 10.1016/s0301-2115(02)00241-5.

Abstract

We describe two cases which demonstrate methotrexate (mtx) to be an effective alternative to surgery in two serious complications of early pregnancy, namely placenta accreta diagnosed at attempted evacuation of retained products of conception and interstitial cornual pregnancy diagnosed at laparoscopy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chorionic Gonadotropin, beta Subunit, Human / blood
  • Female
  • Gestational Age
  • Humans
  • Leucovorin / therapeutic use
  • Methotrexate / therapeutic use*
  • Placenta Accreta / drug therapy*
  • Pregnancy
  • Pregnancy, Ectopic / drug therapy*
  • Treatment Outcome

Substances

  • Chorionic Gonadotropin, beta Subunit, Human
  • Leucovorin
  • Methotrexate